What genetic tests are available for prostate cancer?
The characteristics of any cell are determined by DNA and cancer is a consequence of abnormalities developing in a cell’s genetic code causing, uncontrolled growth. Mutations give cancer cells inappropriate functions and abilities to grow and thrive in parts of your body where they shouldn’t be able to exist.
That makes cancer a genetic disease.
In the future, we hope to be able to tell you whether your cancer is set to spread, or if it has already, using non-invasive genomics testing. Currently, there are blood or saliva tests to deliver assessments. Sometimes, these can guide us as to which treatments your cancer may respond well to.
- Genomics can help us see how close your cells are to gaining all the capabilities they need to become dangerous.
- Some tests under assessment look for rogue by-products that are released by cells when they’re rapidly dividing. You can think of these as something like exhaust fumes from a car that’s over-revving.
- Other tests look for the inability of cells to have the DNA repair mechanisms that would usually prevent mutations from accumulating dangerously.
Genomics is extremely complex and currently there are only a limited number of clinically available tests in the UK, such as:
- BRCA 1 or BRCA 2 blood or saliva test
- Lynch syndrome genes
- A Stockholm 3 blood test
- Proclarix
- Polygenic risk scores
- PDL 1 expression
The BPS team is constantly assessing cutting-edge genomics advances. We believe that these treatments will offer great improvements in cancer diagnosis, prognosis and, therefore, treatment selection within the next few years:
- Decipher genetic mapping
- Oncotype DX
- Prolaris
- MicroRNA (miRNA) analysis
- Proclarix protein blood test
We can’t wait for these tests to come to clinical use. Watch this space.
Ready to take the next step?
If you have worrying symptoms you’d like to get checked, need a second opinion or just want a free chat with one of our nurse specialists, get in touch. Our friendly team will take care of the rest.